منابع مشابه
G-Quadruplex Nucleic Acids
1 IRB Barcelona, IQAC-CSIC, Jordi Girona 16-26, 08034 Barcelona, Spain 2 2 INSERM U869, Laboratoire ARNA, Université de Bordeaux 2, Institut Européen de Chimie-Biologie, 2 rue Robert Escarpit, 33607 Pessac Cedex, France 3Dipartimento di Chimica Organica e Biochimica, Università degli Studi di Napoli “Federico II”, I-80126 Naples, Italy 4 Faculty of Mechanical Engineering, University of Maribor,...
متن کاملGuanine base stacking in G-quadruplex nucleic acids
G-quadruplexes constitute a class of nucleic acid structures defined by stacked guanine tetrads (or G-tetrads) with guanine bases from neighboring tetrads stacking with one another within the G-tetrad core. Individual G-quadruplexes can also stack with one another at their G-tetrad interface leading to higher-order structures as observed in telomeric repeat-containing DNA and RNA. In this study...
متن کاملReporter assays for studying quadruplex nucleic acids.
DNA and RNA G-quadruplexes have gained increasing attention due to their potential role in a wide range of biological functions. The majority of functional studies characterize the influence of quadruplexes in gene expression including transcription and translation. Many of these studies have used reporter assays to elucidate the effect of quadruplexes at certain positions in promoters and untr...
متن کاملNMR methods for studying quadruplex nucleic acids.
Solution NMR spectroscopy has traditionally played a central role in examining quadruplex structure, dynamics, and interactions. Here, an overview is given of the methods currently applied to structural, dynamics, thermodynamics, and kinetics studies of nucleic acid quadruplexes and associated cations.
متن کاملDevelopment of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids.
A tailor-made colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids was developed by incorporating a coumarin-hemicyanine fluorophore into an isaindigotone framework. The significant and distinct changes in both the color and fluorescence of this probe enable the label-free and visual detection of G-quadruplex structures.
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ژورنال
عنوان ژورنال: Journal of Nucleic Acids
سال: 2010
ISSN: 2090-021X
DOI: 10.4061/2010/147650